Suckerin
| Suckerin | |||||||
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| Organism | |||||||
| Symbol | Suckerin-1 | ||||||
| UniProt | A0A081DU69 | ||||||
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Suckerins are a type of block copolymer protein that forms the teeth of sucker rings and beaks of cephalopods.[1][2] These biopolymers form exhibit high elastic modulus and thermoplastic behavior.[3]
Properties
[edit]Suckerin proteins have a size range from 5-60kDA with an isoelectric point of pl 7–10.[1]
Applications
[edit]Suckerin has a structure similar to spider silk. In the future it could be used to make medical tools, specialty bandages, sutures and artificial ligaments. Additionally, it could be used for commercial and industrial products such as well as body armor, parachutes, sails and airplane components.[4] Compared to other natural protein-based materials, suckerins offer advantages in terms of mechanical strength, the ability to form robust supramolecular structures, biocompatibility, excellent thermoplastic property and underwater adhesion, making them suitable for wound healing and various biomedical applications.[5]
References
[edit]- 1 2 Hershewe JM, Wiseman WD, Kath JE, Buck CC, Gupta MK, Dennis PB, et al. (December 2020). "Characterizing and Controlling Nanoscale Self-Assembly of Suckerin-12" (PDF). ACS Synthetic Biology. 9 (12): 3388–3399. doi:10.1021/acssynbio.0c00442. PMID 33201684. S2CID 227039101.
- ↑ Ping, Yuan; Ding, Dawei; Ramos, Ricardo A. N. S.; Mohanram, Harini; Deepankumar, Kanagavel; Gao, Jianqing; Tang, Guping; Miserez, Ali (2017-05-23). "Supramolecular β-Sheets Stabilized Protein Nanocarriers for Drug Delivery and Gene Transfection". ACS Nano. 11 (5): 4528–4541. doi:10.1021/acsnano.6b08393. ISSN 1936-0851.
- ↑ Hiew SH, Sánchez-Ferrer A, Amini S, Zhou F, Adamcik J, Guerette P, et al. (December 2017). "Squid Suckerin Biomimetic Peptides Form Amyloid-like Crystals with Robust Mechanical Properties". Biomacromolecules. 18 (12): 4240–4248. doi:10.1021/acs.biomac.7b01280. PMID 29112414.
- ↑ Kumar A, Kannan S, Lescar J, Verma C, Miserez A (2016). "Squid's Suckerin Proteins in Bits & Bytes". Biophysical Journal. 110 (3): 341a. Bibcode:2016BpJ...110..341K. doi:10.1016/j.bpj.2015.11.1835. ISSN 0006-3495.
- ↑ Hiruthyaswamy, Samson Prince; Deepankumar, Kanagavel (2025). "Suckerin based biomaterials for wound healing: a comparative review with natural protein-based biomaterials". Materials Advances. 6 (4): 1262–1277. doi:10.1039/D4MA01005A. ISSN 2633-5409.
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