Mephenaqualone
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| Clinical data | |
|---|---|
| Routes of administration | Oral[1][2] |
| Drug class | Sedative; Hypnotic; Anxiolytic |
| ATC code |
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| Pharmacokinetic data | |
| Onset of action | 20 minutes[1][2] |
| Duration of action | ~4–10 hours[1] |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C22H18N2O2 |
| Molar mass | 342.398 g·mol−1 |
| 3D model (JSmol) | |
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Mephenaqualone is an analogue of the sedative and hypnotic drug methaqualone which has been sold as a designer drug.[1] It was reported in Germany in 2025 as a contributor to drug overdose cases but has otherwise been little studied. Anecdotal reports suggest it is considerably more potent than methaqualone with a potency similar to that of benzodiazepine derivatives, but no pharmacological data is available as yet.[1][3][4][5] It is reported to have a dose of 0.7–0.8 mg or 2 mg orally and to produce sedative, hypnotic, euphoric, anxiolytic, and pro-sexual effects among others.[1][2] Its onset is 20 minutes and its duration is approximately 4 to 10 hours.[1][2]
See also
[edit]References
[edit]- 1 2 3 4 5 6 7 Wachełko O, Tusiewicz K, Zawadzki M, Szpot P (June 2026). "Reinventing quaaludes: a comprehensive review of designer methaqualone analogs". Forensic Toxicol. doi:10.1007/s11419-026-00773-4. PMID 42289025.
- 1 2 3 4 "Мефенаквалон (Mephenaqualone)". АИПСИН (in Russian). Retrieved 11 July 2026.
- ↑ Yurchenko R, Yurchenko L, Pavelets Y, Galetskaya I, Navitski M, Piatsetskaya A (July 2024). Psychoactive products market observation. Trend analysis. Recent trends in the field of psychoactive substance identification. p. 11.
- ↑ "450. Мефенаквалон Раздел I.A. Вещества с подтвержденной структурой" [Mephenaqualone Section I.A. Structure-Confirmed Substances]. AIPSIN (in Russian).
- ↑ "Warnmeldung. Lebensgefahr durch hochpotente synthetische Opioide in Bayern" [Warning. Life-threatening danger from highly potent synthetic opioids in Bavaria.] (PDF). Bayerische Akademie für Sucht-und Gesundheitsfragen [Bavarian Academy for Addiction and Health Issues] (in German). 2025.
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